There was at least 1 vehicle smoking at this scene- possibly on fire and possibly up to 4 vehicles involved.
A CSW reporter at the scene said there was "a possible fatality here- several seriously injured" and that "extrication was needed" to get some victims out of crashed vehicles.
It appeared that "this was a cross-over crash" as at least one vehicle had "struck and severed the (protective) median cables."
Traffic is affected both north and southbound on I-435 between 87th Street and Gregory Boulevard.
Southbound I-435 was closed at Gregory Boulevard.
There have been two non life-threatening patients transported from the scene: "a 61-year-old driver" of "a pickup truck" and his "57-year-old female passenger.
Both were reportedly seat-belted and the air bags did go off in the pickup and were taken to a south KC-MO medical trauma center.
KC-MO Police have confirmed that there was a fatality at this crash scene.
Additional patients- conditions unknown- were said by KC-MO EMS to be transported to Centerpoint and Children's Mercy hospitals.
Police have no estimate when southbound I-435 will be re-opened south of Gregory.